Kamagra Polo is marketed as a chewable form of sildenafil, a phosphodiesterase type-5 (PDE5) inhibitor used for erectile dysfunction (ED). Because formulations can vary by manufacturer and country, it is important to verify the active ingredient and strength on the product packaging before use. Sildenafil must not be taken with nitrate medicines, such as nitroglycerin or isosorbide, because the combination can cause a dangerous decrease in blood pressure. It may also interact with certain alpha-blockers, blood-pressure medicines, and other ED treatments.